Addition of Eicosapentaenoic Acid to γ-Linolenic Acid–Supplemented Diets Prevents Serum Arachidonic Acid Accumulation in Humans

Relationship between arteriosclerosis obliterans and the ratio of serum eicosapentaenoic acid to arachidonic acid.

PURPOSE A low ratio of serum eicosapentaenoic acid to arachidonic acid (EPA/AA) has been associated with coronary artery disease. We retrospectively examined serum concentrations of polyunsaturated fatty acids in patients with arteriosclerosis obliterans (ASO) and in non-atherosclerotic patients. METHODS From April 2011 to March 2012, serum EPA/AA was retrospectively examined in 33 consecutiv...

Serum eicosapentaenoic acid to arachidonic acid ratio is associated with cardio-healthy exceptional longevity.

Low serum eicosapentaenoic acid / arachidonic acid ratio in male subjects with visceral obesity

BACKGROUND Visceral fat accumulation is caused by over-nutrition and physical inactivity. Excess accumulation of visceral fat associates with atherosclerosis. Polyunsaturated fatty acids have an important role in human nutrition, but imbalance of dietary long-chain polyunsaturated fatty acids, especially low eicosapentaenoic acid (EPA) / arachidonic acid (AA) ratio, is associated with increased...

Evaluating the effect of arachidonic acid and eicosapentaenoic acid on induction of adipogenesis in human adipose-derived stem cells

Objective(s): Adipose tissue is one of the most important endocrine organs that liberates many metabolic mediators such as hormones, cytokines, and chemokines. Different types of fatty acids have key roles in adipogenesis. The aim of this study was to evaluate the effects of two essential fatty acids, including Arachidonic acid (AA) and Eicosapentaenoic acid (EPA), on ...

Association of a Low Serum Eicosapentaenoic Acid/Arachidonic Acid Ratio with the Risk of Acute Venous Thromboembolism